This Doctor Knows How to Find the Root Cause of Your Medical Problems | Paul Saladino

Last updated: Jun 1, 2023

The video is an interview with Dr. Paul Saladino, a certified functional medicine practitioner, discussing his unconventional path to medicine and his appreciation for the impact of nutrition on overall well-being, as well as his exploration of philosophy, Buddhism, and meditation.

The video features an interview with Dr. Paul Saladino, a certified functional medicine practitioner who completed his medical residency in psychiatry at the University of Washington. He talks about his unconventional path to becoming a doctor, which involved spending time exploring the backcountry of the southwestern United States and the wilds of New Zealand. He also discusses his interest in Buddhism and meditation, and how these practices have impacted his spirituality and approach to medicine. Saladino emphasizes the importance of nutrition in overall well-being and encourages people to find the root cause of their medical problems rather than just treating symptoms.

  • Dr. Paul Saladino completed his medical residency in psychiatry and gained an appreciation for the impact of nutrition on overall well-being.
  • He has a deep interest in philosophy, Buddhism, and meditation and believes that exploring these areas can help us find meaning in our lives.
  • Dr. Saladino believes that exploring nature can help us find our place in the universe and bring clarity to our lives.
  • He believes that philosophy and Buddhism are the natural continuum beyond quantum questions and can help us find clarity and meaning in our lives.
  • Dr. Saladino returned to medicine and believes in finding the root cause of medical problems rather than just treating symptoms.
  • He believes that nutrition is the foundation of health and that it is essential to address before anything else.
  • Food is a signal and information going into our bodies and is the biggest lever for health and disease.
  • Plants contain anti-nutrients, and grass-fed meat has more nutrients and molecules that are beneficial for our bodies.
  • Experiential evidence shows that there is more to food than just macronutrient content, and a reductionist perspective misses the immunologic and hormonal response to foods.

This Doctor Knows How to Find the Root Cause of Your Medical Problems | Paul Saladino - YouTube

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Dr. Paul Saladino's Unconventional Path to Medicine

  • Dr. Saladino completed his medical residency in psychiatry at the University of Washington.
  • He participated in ultra marathons and spent two years hiking and skiing the Tetan Mountains of Wyoming.
  • He explored the back country of the southwestern United States and the wilds of New Zealand.
  • He gained a powerful appreciation for the impact that nutrition plays on our strength, endurance, and overall well-being.
  • He took time off before getting his MD to explore and understand where he could find meaning.
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Dr. Saladino's Interest in Philosophy, Buddhism, and Meditation

  • Dr. Saladino got interested in philosophy, Buddhism, and meditation in college.
  • He found a ton of benefit in exploring Eastern philosophy.
  • He resonated with Buddhism's concepts of non-impermanence and suffering and how to release suffering.
  • He found mindfulness as the first piece of that and mindfulness leading to compassion and empathy.
  • He started meditating as a 19 or 20 year old and it was the beginning of a lot of learning for him.
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The Impact of Nature on Dr. Saladino's Life

  • Dr. Saladino grew up in a pretty normal household in suburban Virginia.
  • He had a little taste of something bigger than him in the natural world growing up.
  • He thinks that humans find some clarity in our meaning and our place in the universe when we stand in front of things that are bigger than us.
  • He explored the back country and gained a powerful appreciation for the impact that nutrition plays on our strength, endurance, and overall well-being.
  • He believes that exploring nature can help us find our place in the universe and bring clarity to our lives.
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This Doctor Knows How to Find the Root Cause of Your Medical Problems | Paul Saladino - YouTube

The Continuum Beyond Quantum Questions

  • Dr. Saladino believes that philosophy and Buddhism are the natural continuum beyond quantum questions.
  • He thinks that expanding the lens and pulling the microscope back can lead to philosophical questions about who we are as humans and what life is about.
  • He believes that exploring meditation and mindfulness can help us find meaning in our lives.
  • He thinks that looking up at the sky and asking "what am I doing here?" can lead to a deeper understanding of our place in the universe.
  • He believes that exploring philosophical questions can help us find clarity and meaning in our lives.
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Dr. Saladino's Love for Nature and Philosophy

  • Dr. Saladino has a deep appreciation for the impact of nature on overall well-being.
  • He was obsessed with Taoism and Laozi and wanted to experience the imagery in Chinese art.
  • Humans find clarity in their meaning and place in the universe when they stand in front of things that are bigger than them.
  • Dr. Saladino wanted to feel small and experience places that were bigger than him.
  • He had no plans for making money and just wanted to explore.
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Dr. Saladino's Return to Medicine

  • Dr. Saladino's intellectual curiosity about what makes people healthy and not healthy rose again after his time in the wilderness.
  • He saw firsthand what the practice of medicine meant as a physician assistant in cardiology.
  • He realized that the medicine he saw was not what he had hoped for and people were not getting better because it was all drug-based and symptom-focused.
  • Dr. Saladino believed that nutrition was what was going to move the needle and food was his biggest leverage as a physician assistant.
  • He thought that the paradigm used for infectious disease was used for the whole rest of medicine, but it doesn't work for chronic disease.
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The Power of Nutrition

  • Dr. Saladino believes that people take in kilograms worth of food, but they only think about the micrograms of drugs they take.
  • Medications are measured in milligrams, which is a thousandth of a gram, while food is measured in kilograms, which is a thousand grams.
  • Ultimately, we are all made up of molecules and run by biochemistry, which is molecules.
  • Whether you take in a milligram quantity of a molecule or a kilogram quantity of food, you are doing the same thing in your body.
  • You are giving your body information and signals, and your body responds with biochemical signals.
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Dr. Saladino's Approach to Medicine

  • Dr. Saladino is a certified functional medicine practitioner.
  • He believes in finding the root cause of medical problems rather than just treating symptoms.
  • He uses a systems-based approach to medicine, which means that he looks at the whole body and how everything is interconnected.
  • Dr. Saladino believes that nutrition is the foundation of health and that it is essential to address before anything else.
  • He believes that the body has an innate ability to heal itself if given the right tools.
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Food as Signal and Information

  • Food is a signal and information going into our bodies.
  • Food is a program that we are loading into the computer of our bodies every day.
  • Food is the biggest lever for health and disease.
  • People push back on the idea that food is a signal and information.
  • Some people say that calories in, calories out is as simple as you could eat pop-tarts all day and take a multivitamin, and it would be the same thing.
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Anti-Nutrients and Micronutrients

  • Plants contain anti-nutrients, and the anti-nutrients themselves cause a problem.
  • Anti-nutrients are a problem in the pop-tart hypothesis.
  • A grass-fed steak and a grain-fed steak can look pretty similarly in terms of macronutrient ratios, but in terms of micronutrients and other molecules, they're completely different.
  • Grass-fed meat will have a higher concentration of nutrients, such as vitamin C, vitamin E, and beta-carotene.
  • Grass-fed meat has more glutathione, which is a major molecular antioxidant policeman in the human body.
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Reductionist Perspective

  • Calories in, calories out is a reductionist perspective.
  • It misses the entire immunologic and hormonal response to foods, which is so nuanced.
  • There's no research to prove that calories in, calories out is valuable.
  • There's no research that can dissect it all out because it's so complicated.
  • For micronutrients, people just give you a multivitamin.
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Experiential Evidence

  • Experientially, people can tell the difference between grass-fed and corn-fed meat.
  • There's something more going on than just macronutrient content.
  • People have microbiome issues that can be affected by what their food ate.
  • Pop-tarts have lots of plant foods and have lots of anti-nutrients in them as well.
  • The devil's in the details, and a grass-fed steak and a grain-fed steak can look pretty similarly in terms of macronutrient ratios, but in terms of micronutrients and other molecules, they're completely different.
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Grass-fed vs Grain-fed Meat

  • Grass-fed meat doesn't contain toxins found in grain-fed meat, such as glyphosate, atrazine, and xerolinone.
  • Glyphosate disrupts the shikimate pathway in bacteria and can disrupt the gut microbiome.
  • Court decisions have ruled in favor of people claiming glyphosate exposure gave them cancer.
  • Atrazine is a lipid-soluble toxin that mimics estrogen in the human body.
  • Grain-fed meat has higher concentrations of glyphosate and xenoestrogens than grass-fed meat.
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Plant Toxins and Flavonoids

  • Plants make small molecules to defend themselves against insects and herbivores.
  • Flavonoids mimic estrogen in the human body and can activate the 17 beta estradiol receptor.
  • Excess estrogen can cause gynecomastia in men and affect the balance of other hormones in women.
  • Plant toxins can affect our hormonal signaling and programming our biology in unexpected ways.
  • The carnivore diet involves eating less and less plants to see if it affects immunologic activation and autoimmune conditions.
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The Carnivore Diet

  • The carnivore diet involves eating only animal products, such as meat, fish, and eggs.
  • Dr. Saladino tried the carnivore diet to see if it would affect his eczema and immunologic activation.
  • He was initially skeptical of the diet due to his functional medicine education emphasizing the value of plants.
  • The carnivore diet clicked for him after hearing Jordan Peterson and his daughter's success with it for their autoimmune conditions.
  • The carnivore diet is controversial and not recommended for everyone, but Dr. Saladino believes it can be a useful tool for some people.
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Dr. Saladino's Approach to Medicine

  • Dr. Saladino takes a functional medicine approach to medicine, focusing on finding the root cause of medical problems.
  • He emphasizes the impact of nutrition on overall well-being and believes that food is a big lever for health.
  • He also explores philosophy, Buddhism, and meditation as tools for personal growth and well-being.
  • He believes in the importance of individual experimentation and iteration to find what works best for each person.
  • He is open to unconventional ideas and approaches to medicine and encourages his patients to be curious and open-minded as well.
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Autoimmune Disease and the Gut

  • Most medical problems outside of hospitals can be seen as autoimmune disease.
  • Inflammation is autoimmune and it's all connected.
  • Autoimmune disease is when the immune system reacts against itself.
  • Eczema and psoriasis are examples of autoimmune disease.
  • Autoimmune disease is caused by antigens in the gut or bacteria in the gut causing the barrier to break down.
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The Gut and the Immune System

  • The gut is a delicate barrier between our self and not self.
  • The microbiome is separated from our immune system by one cell layer.
  • The majority of our defense system is in a layer called the lamina propria.
  • Autoimmune disease is triggered when the immune system gets activated and goes on alert.
  • Everyone has different susceptibilities to that activated immune system.
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Ancestral Perspective on Nutrition

  • Humans have only been doing agrarian societies for about 10 to 12,000 years.
  • Stable nitrogen isotope studies of collagen show that people were essentially carnivores.
  • Two million years ago, humans were homo erectus and homo habilis and were essentially carnivores.
  • Our brain size had a logarithmic uptick two million years ago.
  • Stone tools were used two million years ago.
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